Matthew Weir

Matthew Weir

Principal Investigator

Biography

Dr. Matthew Weir is an Associate Professor at Schulich School of Medicine & Dentistry and the newly appointed Dr. Adam Linton Chair in Kidney Health Analytics. He holds key clinical leadership roles as the Medical Director of the Kidney Care Centre and the Hemodialysis Unit at University Hospital, London Health Sciences Centre. With an MSc in Epidemiology and Biostatistics, Dr. Weir specializes in health administrative database research, collaborating with the Ontario Renal Network to improve kidney care through integrated knowledge translation.

Active studies

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No active studies currently linked to this researcher.

Publications (last 3 years)

35 found
202516 items

Risk for Scrotal Surgery After Laparoscopic Donor Nephrectomy : A Population-Based Cohort Study.

Garg AX, McArthur E, Sontrop JM, Boudville N, Connaughton DM, Cuerden MS, Feldman LS, Lam NN, Lentine KL, Nguan C, Parikh CR, Segev DL, Sener A, Smith G, Wang C, Weir MA, Yohanna S, Young A, Naylor KL

Ann Intern Med • 2025

Validity of the International Classification of Diseases, 10th Revision codes for lithium toxicity in adult patients at hospital admission: a cohort study in Canada.

Ahmadi F, Muanda FT, Ehiwario J, McArthur E, Jandoc R, Slater J, Vasudev A, Weir MA, Clark EG, Rej S, Herrmann N, Garg AX

BMJ Open • 2025

High-Throughput Computing to Detect Harmful Drug-Drug Interactions in Older Adults: Protocol for a Population-Based Cohort Study.

Rostamzadeh N, Sharma R, Abdullah SS, McArthur E, Chalabianloo N, Sontrop JM, Weir MA, Sedig K, Garg AX, Muanda FT

JMIR Res Protoc • 2025

Cost-Utility Analysis of Accelerated and Standard Strategies for Renal Replacement Therapy Initiation.

Round J, Akpinar I, Yan C, Patel N, van Katwyk S, Montgomery C, Wald R, Bagshaw SM, STARRT-AKI Investigators

JAMA Netw Open • 2025

PRevEnting FracturEs in REnal Disease-1 (PREFERRED-1): protocol for a pilot study of a pragmatic, randomised controlled trial of denosumab for the prevention of fragility fractures in haemodialysis.

Clemens KK, Cowan A, Dixon S, Naylor K, Weir MA, Thain J, Khan T, Silver S, Molnar AO, Sultan N, Holden RM, Hiremath S, Wald R, Kitchlu A, Arnold J, Field B, Garg AX

BMJ Open • 2025

Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial.

Walsh M, Collister D, Gallagher M, Mark PB, de Zoysa JR, Tyrwhitt J, Tennankore K, Reis G, Xavier D, Liu WJ, Zuo L, Wang AY, Félix C, Sola L, Arici M, Villanueva R, Jha V, Précoma D, Rabbat CG, Alavudeen SS, Faruqui AR, López-Flecher M, Pyne L, Wald R, Yuan F, Balasubramanian K, Lee SF, Kuptsova A, Christou C, Devereaux PJ, ACHIEVE Investigators

Lancet • 2025

Adverse events with co-prescription of angiotensin receptor blockers and clarithromycin compared to azithromycin: A population-based retrospective cohort study.

Tonial NC, Bota SE, Kang Y, Muanda FT, Urquhart BL, Weir MA

Pharmacotherapy • 2025

Clinical Outcomes and Health Care Utilization in Patients with Advanced Chronic Kidney Disease not on Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada.

Wang C, Kang Y, Dixon SN, Jeyakumar N, Scott Brimble K, Garg AX, Blake PG, Stukel TA, Oliver MJ, Al-Jaishi A, Clemens KK, Fu L, Ip J, McKenzie S, Moist L, Molnar AO, Muanda-Tsobo F, Reich M, Roshanov P, Silver SA, Wald R, Weir MA, Yau K, Young A, Naylor KL

Can J Kidney Health Dis • 2025

Lorundrostat in Participants With Uncontrolled Hypertension and Treatment-Resistant Hypertension: The Launch-HTN Randomized Clinical Trial.

Saxena M, Laffin L, Borghi C, Fernandez Fernandez B, Ghali JK, Kopjar B, Polu K, Roger SD, Slingsby BT, Strutz F, Vogt L, Weir MR, Rodman D, Launch-HTN Investigators

JAMA • 2025

Variation in Kidney Transplant Referral, Living Donor Contacts, Waitlisting, and Kidney Transplant Across Regional Renal Programs in Ontario, Canada: A Population-Based Cohort Study.

Naylor KL, Yohanna S, Smith G, Garg AX, Elliott L, Knoll G, Kim SJ, Weir M

Can J Kidney Health Dis • 2025

SGLT2 Inhibitors and Risk for Hyperkalemia Among Individuals Receiving RAAS Inhibitors.

Wing S, Ray JG, Yau K, Jeyakumar N, Abdullah S, Luo B, Cherney DZI, Harel Z, Hundemer GL, Mavrakanas TA, Molnar AO, Odutayo A, Perl J, Young A, Charytan D, Weir M, Wald R

JAMA Intern Med • 2025

Genetic Testing in Adults over 50 Years with Chronic Kidney Disease: Diagnostic Yield and Clinical Implications in a Specialized Kidney Genetics Clinic.

Schott C, Alajmi M, Bukhari M, Relouw S, Wang J, McIntyre AD, Baker C, Colaiacovo S, Campagnolo C, Almada Offerni G, Blake PG, Chiu M, Cowan A, Garg AX, Gunaratnam L, House AA, Huang SS, Iyer H, Jain AK, Jevnikar AM, Johnson J, Lotfy K, Moist L, Rehman F, Roshanov PS, Sultan N, Weir MA, Basharat P, Florendo-Cumbermack A, Khan T, Thain J, Kidd K, Kmoch S, Bleyer AJ, Bhangu J, Hegele RA, Connaughton DM

Genes (Basel) • 2025

Clinical Outcomes and Healthcare Utilization in Patients Receiving Maintenance Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada.

Naylor KL, Jeyakumar N, Kang Y, Dixon SN, Garg AX, Al-Jaishi A, Blake PG, Chanchlani R, Fu L, Harel Z, Ip J, Kitchlu A, Kwong JC, Nesrallah G, Oliver MJ, Stukel TA, Wald R, Weir M, Yau K

Can J Kidney Health Dis • 2025

Time to Renal Replacement Therapy Initiation in Critically Ill Patients With Acute Kidney Injury: A Secondary Analysis of the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial.

Jeong R, Bagshaw SM, Ghamarian E, Harvey A, Joannidis M, Kirkham B, McAuley D, Ostermann M, Quenot JP, Young PJ, Wald R, STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Investigators

Crit Care Med • 2025

Implementation of a Kidney Genetic Service Into the Diagnostic Pathway for Patients With Chronic Kidney Disease in Canada.

Schott C, Arnaldi M, Baker C, Wang J, McIntyre AD, Colaiacovo S, Relouw S, Offerni GA, Campagnolo C, Van Nynatten LR, Pourtousi A, Drago-Catalfo A, Lebedeva V, Chiu M, Cowan A, Filler G, Gunaratnam L, House AA, Huang S, Iyer H, Jain AK, Jevnikar AM, Lotfy K, Moist L, Rehman F, Roshanov PS, Sharma AP, Weir MA, Kidd K, Bleyer AJ, Hegele RA, Connaughton DM

Kidney Int Rep • 2025

Anticoagulation for Patients with Atrial Fibrillation Receiving Dialysis: A Pilot Randomized Controlled Trial.

Harel Z, Smyth B, Badve SV, Blum D, Beaubien-Souligny W, Silver SA, Clark E, Suri R, Mavrakanas TA, Sasal J, Prasad B, Eikelboom J, Tennankore K, Rigatto C, Prce I, Madore F, Mac-Way F, Steele A, Zeng Y, Sholzberg M, Dorian P, Yan AT, Sood MM, Gladstone DJ, Tseng E, Kitchlu A, Walsh M, Sapir D, Oliver MJ, Krishnan M, Kiaii M, Wong N, Kotwal S, Battistella M, Acedillo R, Lok C, Weir M, Wald R

J Am Soc Nephrol • 2025

202411 items

The Global Kidney Patient Trials Network and the CAPTIVATE Platform Clinical Trial Design: A Trial Protocol.

Kotwal SS, Perkovic V, Jardine MJ, Kim D, Shah NA, Lin E, Coggan S, Billot L, Vart P, Wheeler DC, de Boer IH, Zhang H, Hou FF, Sugawara Y, Marion J, Lewis RJ, Berry LR, McGlothlin A, Jha V, De Nicola L, Gorriz JL, Heerspink HJL, GKPTN and CAPTIVATE Investigators

JAMA Netw Open • 2024

Higher dose antiviral therapy for herpes infections is associated with a risk of serious adverse events in older adults with chronic kidney disease.

Olar P, Garg AX, Weir MA, Ahmadi F, McArthur E, Lam NN, Sontrop JM, Muanda FT

Pharmacol Res Perspect • 2024

An Environmental Scan of Canadian Kidney Transplant Programs for the Management of Patients With Graft Failure: A Research Letter.

Slominska A, Gaudio K, Shamseddin MK, Lam NN, Ho J, Vinson A, Mainra R, Hoar S, Fortin MC, Kim SJ, DeSerres S, Prasad GVR, Weir MA, Cantarovich M, Sandal S

Can J Kidney Health Dis • 2024

Vascular calcification in chronic kidney disease associated with pathogenic variants in ABCC6.

Schott C, Dilliott AA, Wang J, McIntyre AD, Son S, Colaiacovo S, Baker C, Gunaratnam L, House AA, Susan Huang SH, Iyer H, Johnson J, Lotfy K, Masellis M, Munoz DP, Rehman F, Roshanov PS, Swartz RH, Weir MA, Hegele RA, Connaughton DM

Gene • 2024

Thirty-day risk of digoxin toxicity among older adults co-prescribed trimethoprim-sulfamethoxazole versus amoxicillin: A population-based cohort study.

Muanda FT, Weir MA, Ahmadi F, McArthur E, Sontrop JM, Abdullah SS, Urquhart BL, Sadeghi H, Kim RB, Garg AX

Pharmacotherapy • 2024

DCRM 2.0: Multispecialty practice recommendations for the management of diabetes, cardiorenal, and metabolic diseases.

Handelsman Y, Anderson JE, Bakris GL, Ballantyne CM, Bhatt DL, Bloomgarden ZT, Bozkurt B, Budoff MJ, Butler J, Cherney DZI, DeFronzo RA, Del Prato S, Eckel RH, Filippatos G, Fonarow GC, Fonseca VA, Garvey WT, Giorgino F, Grant PJ, Green JB, Greene SJ, Groop PH, Grunberger G, Jastreboff AM, Jellinger PS, Khunti K, Klein S, Kosiborod MN, Kushner P, Leiter LA, Lepor NE, Mantzoros CS, Mathieu C, Mende CW, Michos ED, Morales J, Plutzky J, Pratley RE, Ray KK, Rossing P, Sattar N, Schwarz PEH, Standl E, Steg PG, Tokgözoğlu L, Tuomilehto J, Umpierrez GE, Valensi P, Weir MR, Wilding J, Wright EE Jr

Metabolism • 2024

Renal Transplantation in HIV-positive and HIV-negative People With Advanced Stages of Kidney Disease: Equity in Transplantation.

Hosseini-Moghaddam SM, Kang Y, Bota SE, Weir MA

Open Forum Infect Dis • 2024

Reclassification of Genetic Testing Results: A Case Report Demonstrating the Need for Structured Re-Evaluation of Genetic Findings.

Schott C, Colaiacovo S, Baker C, Weir MA, Connaughton DM

Can J Kidney Health Dis • 2024

Regional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.

Vaara ST, Serpa Neto A, Bellomo R, Adhikari NKJ, Dreyfuss D, Gallagher M, Gaudry S, Hoste E, Joannidis M, Pettilä V, Wang AY, Kashani K, Wald R, Bagshaw SM, Ostermann M, STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Investigators

Crit Care Explor • 2024

Impact of Donation After Circulatory Death on Outcomes of Expanded Criteria Donor Kidney Transplants.

Alsolami E, Lotfy K, Alkhunaizi A, Cuerden M, Weir MA, House AA

Transplant Proc • 2024

High-Throughput Computing to Automate Population-Based Studies to Detect the 30-Day Risk of Adverse Outcomes After New Outpatient Medication Use in Older Adults with Chronic Kidney Disease: A Clinical Research Protocol.

Abdullah SS, Rostamzadeh N, Muanda FT, McArthur E, Weir MA, Sontrop JM, Kim RB, Kamran S, Garg AX

Can J Kidney Health Dis • 2024

20238 items

Low-Dose Methotrexate and Serious Adverse Events Among Older Adults With Chronic Kidney Disease.

Muanda FT, Blake PG, Weir MA, Ahmadi F, McArthur E, Sontrop JM, Urquhart BL, Kim RB, Garg AX

JAMA Netw Open • 2023

Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial.

Wald R, Gaudry S, da Costa BR, Adhikari NKJ, Bellomo R, Du B, Gallagher MP, Hoste EA, Lamontagne F, Joannidis M, Liu KD, McAuley DF, McGuinness SP, Nichol AD, Ostermann M, Palevsky PM, Qiu H, Pettilä V, Schneider AG, Smith OM, Vaara ST, Weir M, Dreyfuss D, Bagshaw SM, STARRT-AKI Investigators

Intensive Care Med • 2023

Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Ku E, Del Vecchio L, Eckardt KU, Haase VH, Johansen KL, Nangaku M, Tangri N, Waikar SS, Więcek A, Cheung M, Jadoul M, Winkelmayer WC, Wheeler DC, for Conference Participants

Kidney Int • 2023

Investigation of N,N,N-Trimethyl-L-alanyl-L-proline Betaine (TMAP) as a Biomarker of Kidney Function.

Sidor NA, Velenosi TJ, Lajoie GA, Filler G, House AA, Weir MA, Thomson BK, Garg AX, Renaud JB, McDowell T, Knauer MJ, Tirona RG, Noble R, Selby N, Taal M, Urquhart BL

ACS Omega • 2023

Hypocalcemia Risk of Denosumab Across the Spectrum of Kidney Disease: A Population-Based Cohort Study.

Cowan A, Jeyakumar N, McArthur E, Fleet JL, Kanagalingam T, Karp I, Khan T, Muanda FT, Nash DM, Silver SA, Thain J, Weir MA, Garg AX, Clemens KK

J Bone Miner Res • 2023

The effect of micro-particle curcumin on chronic kidney disease progression: the MPAC-CKD randomized clinical trial.

Weir MA, Walsh M, Cuerden MS, Sontrop JM, Urquhart BL, Lim YJ, Chambers LC, Garg AX

Nephrol Dial Transplant • 2023

Correction: Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial.

Bagshaw SM, Neto AS, Smith O, Weir M, Qiu H, Du B, Wang AY, Gallagher M, Bellomo R, Wald R, STARRT-AKI Investigators

Intensive Care Med • 2023

Trimethoprim-sulfamethoxazole and the risk of a hospital encounter with hyperkalemia: a matched population-based cohort study.

Hwang YJ, Muanda FT, McArthur E, Weir MA, Sontrop JM, Lam NN, Garg AX

Nephrol Dial Transplant • 2023

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