Kidney care through research.
We conduct clinical studies to improve the lives of people with kidney disease.
RECRUITING
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure (BaxDuo-Pacific)
Recent research
Randomized Controlled Trial of Intradialytic Cycling as Kidney Exercise Rehabilitation for Cardiac Stunning in Hemodialysis (TICKERS_HD): A Clinical Research Protocol.
Can J Kidney Health Dis
Christopher McIntyre
Caution in extending SGLT2 inhibitor trials to children with CAKUT: a call for phenotype-specific safety considerations.
Pediatr Nephrol
Christopher McIntyre
Endothelial Injury to Cognitive Decline: A 12-month Follow-up Using CT-Perfusion and Diffusion MRI in Immune-mediated Thrombotic Thrombocytopenic Purpura.
J Thromb Haemost
Susan Huang
Genetic Testing in Adults over 50 Years with Chronic Kidney Disease: Diagnostic Yield and Clinical Implications in a Specialized Kidney Genetics Clinic.
Genes (Basel)
Louise Moist, Dervla Connaughton, Matthew Weir, Susan Huang, Andrew House, Lakshman Gunaratnam, Arsh Jain, Amit Garg, Andrea Cowan, Pavel Roshanov, Peter Blake
Clinical Outcomes and Health Care Utilization in Patients with Advanced Chronic Kidney Disease not on Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada.
Can J Kidney Health Dis
Louise Moist, Matthew Weir, Kyla Naylor, Amit Garg, Pavel Roshanov, Peter Blake
Frequency, Management, and Outcomes of Outpatient Hyperkalemia: A Population-Based Cohort Study.
Can J Kidney Health Dis
Louise Moist, Arsh Jain, Danielle Nash, Amit Garg
Risk for Scrotal Surgery After Laparoscopic Donor Nephrectomy : A Population-Based Cohort Study.
Ann Intern Med
Dervla Connaughton, Matthew Weir, Kyla Naylor, Amit Garg
Clinical Outcomes and Healthcare Utilization in Patients Receiving Maintenance Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada.
Can J Kidney Health Dis
Matthew Weir, Kyla Naylor, Amit Garg, Peter Blake
PRevEnting FracturEs in REnal Disease-1 (PREFERRED-1): protocol for a pilot study of a pragmatic, randomised controlled trial of denosumab for the prevention of fragility fractures in haemodialysis.
BMJ Open
Matthew Weir, Kyla Naylor, Amit Garg, Andrea Cowan
Variation in Kidney Transplant Referral, Living Donor Contacts, Waitlisting, and Kidney Transplant Across Regional Renal Programs in Ontario, Canada: A Population-Based Cohort Study.
Can J Kidney Health Dis
Matthew Weir, Kyla Naylor, Amit Garg
Process Evaluation Alongside a Cluster-Randomized Trial of a Multicomponent Intervention Designed to Improve Patient Access to Kidney Transplantation.
Can J Kidney Health Dis
Kyla Naylor, Amit Garg, Peter Blake
Cultivating Innovative, Pragmatic, Randomized Controlled Registry Trials Embedded in Hemodialysis Care: Conference Proceeding From Gardener's Grove 2023.
Can J Kidney Health Dis
Amit Garg, Pavel Roshanov, Peter Blake
Approximating the Proportion of Individuals With Kidney Failure Who Die Without Kidney Replacement Therapy in Ontario, Canada.
Can J Kidney Health Dis
Amit Garg, Andrea Cowan, Peter Blake
Outcomes of Adopting a Higher Versus Lower Concentration of Hemodialysate Magnesium as a Center-Wide Policy (Dial-Mag): A Clinical Research Protocol of a Pragmatic, Registry-Based, Cluster Randomized Trial.
Can J Kidney Health Dis
Amit Garg, Andrea Cowan, Peter Blake
Dialysis and cognitive impairment.
Nat Rev Nephrol
Christopher McIntyre, Arsh Jain
The Flow of Living Kidney Donor Candidates Through the Evaluation Process: A Single-Center Experience in Ontario, Canada.
Can J Kidney Health Dis
Dervla Connaughton, Amit Garg
Adverse events with co-prescription of angiotensin receptor blockers and clarithromycin compared to azithromycin: A population-based retrospective cohort study.
Pharmacotherapy
Matthew Weir, Brad Urquhart
Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial.
Lancet
Matthew Weir, Pavel Roshanov
High-Throughput Computing to Detect Harmful Drug-Drug Interactions in Older Adults: Protocol for a Population-Based Cohort Study.
JMIR Res Protoc
Matthew Weir, Amit Garg
Validity of the International Classification of Diseases, 10th Revision codes for lithium toxicity in adult patients at hospital admission: a cohort study in Canada.
BMJ Open
Matthew Weir, Amit Garg
Randomized Controlled Trial of Intradialytic Cycling as Kidney Exercise Rehabilitation for Cardiac Stunning in Hemodialysis (TICKERS_HD): A Clinical Research Protocol.
Can J Kidney Health Dis
Christopher McIntyre
Caution in extending SGLT2 inhibitor trials to children with CAKUT: a call for phenotype-specific safety considerations.
Pediatr Nephrol
Christopher McIntyre
Endothelial Injury to Cognitive Decline: A 12-month Follow-up Using CT-Perfusion and Diffusion MRI in Immune-mediated Thrombotic Thrombocytopenic Purpura.
J Thromb Haemost
Susan Huang
Genetic Testing in Adults over 50 Years with Chronic Kidney Disease: Diagnostic Yield and Clinical Implications in a Specialized Kidney Genetics Clinic.
Genes (Basel)
Louise Moist, Dervla Connaughton, Matthew Weir, Susan Huang, Andrew House, Lakshman Gunaratnam, Arsh Jain, Amit Garg, Andrea Cowan, Pavel Roshanov, Peter Blake
Clinical Outcomes and Health Care Utilization in Patients with Advanced Chronic Kidney Disease not on Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada.
Can J Kidney Health Dis
Louise Moist, Matthew Weir, Kyla Naylor, Amit Garg, Pavel Roshanov, Peter Blake
Frequency, Management, and Outcomes of Outpatient Hyperkalemia: A Population-Based Cohort Study.
Can J Kidney Health Dis
Louise Moist, Arsh Jain, Danielle Nash, Amit Garg
Risk for Scrotal Surgery After Laparoscopic Donor Nephrectomy : A Population-Based Cohort Study.
Ann Intern Med
Dervla Connaughton, Matthew Weir, Kyla Naylor, Amit Garg
Clinical Outcomes and Healthcare Utilization in Patients Receiving Maintenance Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada.
Can J Kidney Health Dis
Matthew Weir, Kyla Naylor, Amit Garg, Peter Blake
PRevEnting FracturEs in REnal Disease-1 (PREFERRED-1): protocol for a pilot study of a pragmatic, randomised controlled trial of denosumab for the prevention of fragility fractures in haemodialysis.
BMJ Open
Matthew Weir, Kyla Naylor, Amit Garg, Andrea Cowan
Variation in Kidney Transplant Referral, Living Donor Contacts, Waitlisting, and Kidney Transplant Across Regional Renal Programs in Ontario, Canada: A Population-Based Cohort Study.
Can J Kidney Health Dis
Matthew Weir, Kyla Naylor, Amit Garg
Process Evaluation Alongside a Cluster-Randomized Trial of a Multicomponent Intervention Designed to Improve Patient Access to Kidney Transplantation.
Can J Kidney Health Dis
Kyla Naylor, Amit Garg, Peter Blake
Cultivating Innovative, Pragmatic, Randomized Controlled Registry Trials Embedded in Hemodialysis Care: Conference Proceeding From Gardener's Grove 2023.
Can J Kidney Health Dis
Amit Garg, Pavel Roshanov, Peter Blake
Approximating the Proportion of Individuals With Kidney Failure Who Die Without Kidney Replacement Therapy in Ontario, Canada.
Can J Kidney Health Dis
Amit Garg, Andrea Cowan, Peter Blake
Outcomes of Adopting a Higher Versus Lower Concentration of Hemodialysate Magnesium as a Center-Wide Policy (Dial-Mag): A Clinical Research Protocol of a Pragmatic, Registry-Based, Cluster Randomized Trial.
Can J Kidney Health Dis
Amit Garg, Andrea Cowan, Peter Blake
Dialysis and cognitive impairment.
Nat Rev Nephrol
Christopher McIntyre, Arsh Jain
The Flow of Living Kidney Donor Candidates Through the Evaluation Process: A Single-Center Experience in Ontario, Canada.
Can J Kidney Health Dis
Dervla Connaughton, Amit Garg
Adverse events with co-prescription of angiotensin receptor blockers and clarithromycin compared to azithromycin: A population-based retrospective cohort study.
Pharmacotherapy
Matthew Weir, Brad Urquhart
Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial.
Lancet
Matthew Weir, Pavel Roshanov
High-Throughput Computing to Detect Harmful Drug-Drug Interactions in Older Adults: Protocol for a Population-Based Cohort Study.
JMIR Res Protoc
Matthew Weir, Amit Garg
Validity of the International Classification of Diseases, 10th Revision codes for lithium toxicity in adult patients at hospital admission: a cohort study in Canada.
BMJ Open
Matthew Weir, Amit Garg


















