Christopher McIntyre

Christopher McIntyre

Principal Investigator

Biography

Dr. McIntyre is Professor of Medicine, Professor of Medical Biophysics, and Professor of Paediatrics and Robert Lindsay Chair of Dialysis Research and Innovation at Western. He also serves as Director of the London Health Sciences Centre Research Institute, where he is also a practicing Clinical Nephrologist. He leads a team of multidisciplinary researchers focused largely on the pathophysiology of the effecting cardiovascular, brain, liver and gastro-intestinal structure and function in patients with chronic kidney disease. These studies include basic clinical science, natural history studies and the development and application of novel therapeutic strategies into large scale randomized controlled trials. These studies have increasingly focused on the adverse consequences resulting from dialysis therapy itself and the improvement in outcomes by the reduction of preventable harm. Multimodal imaging plays an important role in these studies including ultrasound, CT, PET and MRI.

Active studies

0 listed

No active studies currently linked to this researcher.

Publications (last 3 years)

16 found
20255 items

Coronary Artery Disease and Intradialytic Myocardial Ischemia in Hemodialysis: An Exploratory Study Using Intradialytic Imaging.

Hur L, Islam A, Penny JD, Dorie J, McIntyre CW

Kidney Med • 2025

Impact of Expanded Hemodialysis on Subjective Experience Using Dynamic Patient-Reported Outcome Measurement Tool.

Penny JD, Gozdzik D, Tamasi T, Dorie J, Koyle K, Lozon ZB, Cesario R, Nesrallah G, McIntyre CW

Kidney Med • 2025

The Effect of Dialysate Sodium on Endothelial Injury and Microcirculatory Dysfunction.

Hur L, Zhang Y, Akbari A, Patterson EK, Janssen BGH, McIntyre CW

Kidney360 • 2025

Development of a Novel Intraperitoneal Icodextrin/Dextrose Solution for Enhanced Sodium Removal.

Asher JL, Ivey-Miranda JB, Maulion C, Cox ZL, Borges-Vela JA, Mendoza-Zavala GH, Cigarroa-Lopez JA, Silva-Rueda RI, Revilla-Monsalve C, Moreno-Villagomez J, Ramos-Mastache D, Goedje O, Crosbie I, McIntyre C, Finkelstein F, Turner JM, Testani JM, Rao VS

Kidney Med • 2025

In vivo assessment of pediatric kidney function using multi-parametric and multi-nuclear functional magnetic resonance imaging: challenges, perspectives, and clinical applications.

De Mul A, Schleef M, Filler G, McIntyre C, Lemoine S

Pediatr Nephrol • 2025

20244 items

(23)NaMRI Assessed Cyst Sodium Concentration in Polycystic Kidney Disease to Identify Cyst Metabolic Activity: A Proof of Concept Study.

Lemoine S, Akbari A, McIntyre CW

Kidney Med • 2024

Redefining the concept of residual renal function with kidney sodium MRI: a pilot study.

Lemoine S, Akbari A, Brahm G, Dorie J, Tamasi T, Penny J, McIntyre CW

Nephrol Dial Transplant • 2024

Effect of Intradialytic Exercise on Cardiovascular Outcomes in Maintenance Hemodialysis: A Systematic Review and Meta-Analysis.

Verrelli D, Sharma A, Alexiuk J, Tays Q, Rossum K, Sharma M, Ford E, Iansavitchene A, Al-Jaishi AA, Whitlock R, McIntyre CW, Garg AX, Bohm C

Kidney360 • 2024

20237 items

A novel multiplex biomarker panel for profiling human acute and chronic kidney disease.

Van Nynatten LR, Miller MR, Patel MA, Daley M, Filler G, Badrnya S, Miholits M, Webb B, McIntyre CW, Fraser DD

Sci Rep • 2023

Non-invasive intradialytic percutaneous perfusion monitoring: a view to the heart through the skin.

Penny JD, Hur L, Salerno FR, Wong D, Jan MH, McIntyre CW

Front Nephrol • 2023

Recent Advances in Sodium Magnetic Resonance Imaging and Its Future Role in Kidney Disease.

Akbari A, McIntyre CW

J Clin Med • 2023

Midodrine Is an Effective Therapy for Resistant Intradialytic Hypotension: PRO.

House AA, McIntyre CW

Kidney360 • 2023

Hemodialysis-Related Acute Brain Injury Demonstrated by Application of Intradialytic Magnetic Resonance Imaging and Spectroscopy.

Anazodo UC, Wong DY, Théberge J, Dacey M, Gomes J, Penny JD, van Ginkel M, Poirier SE, McIntyre CW

J Am Soc Nephrol • 2023

Effects of pediatric chronic kidney disease and its etiology on tissue sodium concentration: a pilot study.

Salerno FR, Akbari A, Lemoine S, Scholl TJ, McIntyre CW, Filler G

Pediatr Nephrol • 2023

Cardiac implications of upper-arm arteriovenous fistulas: A case series.

Pucchio A, McIntyre C, Lok C, Moist L

J Vasc Access • 2023

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