Fluid Intake After Hemodialysis

NCT04721652Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sChristopher McIntyreChristopher McIntyre

Actively Recruiting

View on ClinicalTrials.gov ↗

About This Study

This observational study investigates the temporal patterns of interdialytic weight gain and blood pressure fluctuations in approximately 20 patients receiving thrice-weekly HD. The study excludes patients with diabetes or significant residual urine volume to minimize osmotic and renal confounders of thirst. Participants perform prospective home monitoring of body weight and blood pressure four times daily for one week while completing validated assessments for xerostomia, thirst perception, and dietary sodium intake. The primary objective is to characterize the relationship between fluid intake timing and the post-dialysis interval to better understand the drivers of ultrafiltration requirements.

Who Can Participate?

✓ Inclusion Criteria

  • •Age ≥ 18 years
  • •Thrice weekly maintenance hemodialysis
  • •Willing and able to provide written informed consent

✗ Exclusion Criteria

  • •Diabetes Mellitus
  • •Residual Urinary Volume > 500 ml/day
  • •Being able to self-monitor one's body weight and blood pressure