Clinical Research

Active Studies

Use the trial matching assistant in the bottom-right corner to narrow down actively recruiting studies.

Manage studies
37 recruiting
5 coming soon
7 active, not recruiting

Filter by area

All(65)Glomerulonephritis(10)Pre-dialysis CKD(15)Polycystic kidney disease(1)Genetic Kidney Disease(7)Hemodialysis(19)Peritoneal dialysis(4)Transplant – eligibility and preparation(1)Transplant – perioperative(3)Transplant – post-transplant care(2)Dialysis vascular access(1)Perioperative care (non-transplant)(1)
Showing 2 studies in Transplant – eligibility and preparation
Coming Soon1 study

Gender and Frailty in Transplantation (GiFT)

Transplant – eligibility and preparation

Louise MoistLouise Moist

The GiFT study is a prospective, multicentre observational cohort study of adults aged 18 to 80 years who recently started hemodialysis or peritoneal dialysis in Canada. Participants undergo objective and subjective frailty assessments within three months of dialysis initiation, including the Fried Frailty Phenotype, Frailty Index, Five Times Sit-to-Stand test, Clinical Frailty Scale, and Pictorial Fit-Frail Scale. The primary objective is to determine whether frailty is associated with reduced or delayed kidney transplant referral and whether this relationship differs by gender. Secondary outcomes include time to transplant work-up completion, waitlist activation, and living donor contact.

Completed1 study

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates (CARSK)

Transplant – eligibility and preparation · University of British Columbia

Lakshman GunaratnamLakshman Gunaratnam

The CARSK trial evaluates whether eliminating routine, non-invasive coronary artery disease (CAD) screening after waitlist activation is non-inferior to standard periodic screening for preventing major adverse cardiac events. The study population consists of asymptomatic kidney transplant candidates with ESRD who have already undergone initial screening for waitlist entry. Participants are randomized to either no further CAD screening until transplantation or regular screening at annual intervals. Secondary outcomes include the rate of transplantation and the relative cost-effectiveness of each strategy. This trial addresses the lack of evidence supporting the current practice of repetitive cardiac testing in patients awaiting renal replacement therapy.